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RCP Medicine PodcastAuthor: Royal College of Physicians
The RCP Medicine podcast is a discussion of different topics relevant to physicians. Episodes discuss and explore different topics including real-life clinical cases, new evidence-based guidelines and specific physician issues in the modern healthcare environment. The views expressed in this podcast are those of the presenters and not necessarily the RCP. Language: en Genres: Education, Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Episode 101: Acute Liver Failure: Differentials, Deterioration and Decisive Action
Tuesday, 24 February, 2026
In this episode of the RCP Medicine Podcast, transplant hepatologist Dr Mhairi Donnelly joins gastroenterology trainee Dr Jennifer Tham to explore the high‑stakes world of acute liver failure.Through a detailed case of a young woman presenting with severe transaminitis and paracetamol toxicity, Mhairi and Jennifer guide listeners through the crucial steps in recognising acute liver injury, identifying early markers of deterioration, and escalating care at the right time.The discussion covers the most common causes of acute liver failure in the UK, how to interpret markedly raised transaminases, the role of NAC beyond confirmed paracetamol toxicity, the importance of monitoring lactate and INR trends, management of hepatic encephalopathy in acute liver failure, and how psychiatric assessment influences transplant suitability. A must‑listen for anyone managing acutely unwell medical patients or seeking to deepen their understanding of this life‑threatening condition.RCP Links Education Events Membership Improving care Policy and campaigns RCP Social Media Instagram LinkedIn Facebook X Bluesky Music: Episode 50 onward - Bensound.com Episodes 1 - 49 'Impressive Deals' - Nicolai Heidlas
