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The Health Edge: translating the science of self-careAuthor: Mark Pettus MD and John Bagnulo PhD, MPH
Its not what we dont know that gets us into trouble. Its what we know that aint so. Will RogersWe believe the explosion of life science research from many disciplines had catapulted ahead of our capacity to process, integrate, understand, and apply. We are interested in translating all that is out there as news to use. A fundamentally different understanding of human biology has emerged. The implications from the perspective of self-care are profound. We are rapidly moving away from the debate of nature versus nurture toward an understanding that life emerges from a dynamic landscape of nature via nurture. We are passionate about the science. We are passionate about the implications. We believe in the capacity and possibility made possible by being alive here and now! We are beautifully designed to be on the African Savannah, living fully integrated with our planet, and in the context of social relationship. Our modern environment is not well designed to promote human health and the capacity to thrive. Many are struggling to maintain balance and traction in lives that often feel overwhelming and frightening.The challenge is to better leverage our superb ancestral adaptation for a different and radically challenging modern environment. Everything that touches us today has the potential be be very familiar or totally foreign. The less aware one is of the day to day distance between what we are biologically , as a species, familiar with and what we actually encounter, the fewer the possibilities for more effective alignment. Leaving ones health trajectory to chance in our modern environment is a very risky proposition. We are interested in holding the science to the light with an open and humbled mindset. Like you, We are intrepid explorers interested in how we emerge in the midst of our relationship with the environmental inputs of our liveshow we eat, how we move, how we sleep, how we navigate the mind fields of conflict in our lives, how socially conn Language: en Genres: Alternative Health, Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Rethinking Alkaline Eating: What Really Drives Metabolic Health
Wednesday, 14 January, 2026
Send us a textForget the hype about a food’s pH in your glass. What shapes your health is the acid produced after digestion—and how your kidneys manage it all day, every day. We unpack the science behind dietary acid load, explain the difference between DAL, PRAL, and NEAP, and show how a modern, grain-heavy pattern quietly raises acid burden while delivering minimal nutrients. The goal isn’t to fear protein; it’s to pair it with the right plants so bones, muscles, and metabolism get stronger together.We walk through how the kidneys buffer acids using ammonium and titratable pathways, why blood pH won’t reflect diet, and how a simple first-morning urine pH can be a practical window into your load. Then we get tactical: spinach, tomatoes, avocados, Swiss chard, and sweet potatoes are heavy hitters for generating bicarbonate and neutralizing the acids that come from protein. We also dig into evidence linking higher PRAL with fatty liver in type 2 diabetes and explore mechanisms that tie low-grade acidosis to insulin resistance and muscle catabolism.If you train hard, there’s a performance angle too. Some athletes use sodium bicarbonate to improve tolerance to lactic acid, and low-PRAL phases show promise for faster lactate clearance. For kidney stone formers, potassium citrate can meaningfully alkalinize urine and improve uric acid handling. The simple blueprint: keep protein adequate, cut refined grains and sugars, and choose alkalinizing plants that support your kidneys. Try a one-week experiment, track your morning pH, and notice how energy, recovery, and clarity respond.If this resonated, follow the show, share with a friend who loves both science and good food, and leave a review to help others find us. Your feedback shapes future episodes.For video, open-source references and powerpoint slide deck go to: www.thehealthedgepodcast.com
