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IM Journal ClubJournal-Clubbing Our Way Through Internal Medicine Author: IM Journal Club Language: en Genres: Health & Fitness, Life Sciences, Medicine, Science Contact email: Get it Feed URL: Get it iTunes ID: Get it Trailer: |
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Doxycycline for Community Acquired Pneumonia w/ Dr. Brad Spellberg
Episode 13
Thursday, 22 December, 2022
Doxycycline is an old tetracycline-like antibiotic with a comparatively good side-effect profile, but it doesn’t get much love in the guidelines for community-acquired pneumonia as the evidence level was deemed to be low. A recent issue of Clinical Infectious Diseases contained a systematic review with a meta-analysis. Dr. Brad Spellberg is the chief medical office at the Los Angeles County-University of Southern California Medical Center. Dr. Spellberg is also a professor of clinical medicine and the associate dean for clinical affairs at the USC’s Keck School of Medicine. I talk with him about why doxy might be a good CAP drug (and when it is not a good choice), guidelines and the process of creating guidelines, and resistance patterns, MICs, and clinical significance. References:-Shorter Is Better: https://www.bradspellberg.com/shorter-is-better -Oral Is the New IV: https://www.bradspellberg.com/oral-antibiotics -WikiGuidelines: https://www.wikiguidelines.com/ -SH Choi et al.: Clin Infect Dis. 2022 Jul 29;ciac615. https://pubmed.ncbi.nlm.nih.gov/35903011/-NICE: Pneumonia (community-acquired): antimicrobial prescribing. Published: 16 September 2019. https://www.nice.org.uk/guidance/ng138-JP Metlay et al. Am J Respir Crit Care Med. 2019 Oct 1;200(7):e45-e67. doi: 10.1164/rccm.201908-1581ST. https://pubmed.ncbi.nlm.nih.gov/31573350/ YouTube channel: https://www.youtube.com/@IMJournalClub Hosted on Acast. See acast.com/privacy for more information.
