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The Retina Channel PodcastAuthor: Keyvan Koushan, MD, FRCSC
A journal club to review recent journal articles in the field of retina. The target audience are retina specialists and other healthcare professionals who want to stay up-to-date with the latest publications in the field of retina. Language: en Genres: Health & Fitness, Life Sciences, Medicine, Science Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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E94 – Systemic Drugs & Underrecognized Maculopathy - Dr. Seong Joon Ahn
Friday, 23 January, 2026
In this episode of The Retina Channel Podcast, I sit down with Dr. Seong Joon Ahn from Hanyang University in South Korea to discuss a recent JAMA Ophthalmology study examining systemic drugs associated with underrecognized maculopathy. Using a novel two-step approach that integrates pharmacovigilance signal detection from the FDA Adverse Event Reporting System (FAERS) with nationwide health-claims data from South Korea, the study identifies several commonly used systemic medications— apixaban, paclitaxel, ibrutinib, fingolimod, and sildenafil—as being associated with an increased risk of maculopathy. We explore the study's methodology, key findings such as dose-response relationships, and the clinical implications for retina specialists and general ophthalmologists alike, particularly around patient counseling and the potential need for ocular monitoring in patients on these medications. Kim J, Ahn SJ, Park J, Gower EW, Chung JE. Systemic drugs associated with maculopathy. JAMA Ophthalmol.2025;143(11):946-952. doi:10.1001/jamaophthalmol.2025.3612.
