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The Health Upgrade PodcastThis podcast is for high-performing entrepreneurs, healthcare professionals, and those who want to upgrade every aspect of their lives by experiencing UPGRADED energy, UPGRADED focus, and UPGRADED ability to show up, every day of their lives. Author: Navaz Habib
This podcast is for high-performing entrepreneurs, healthcare professionals, and those who want to upgrade every aspect of their lives by experiencing UPGRADED energy, UPGRADED focus, and UPGRADED ability to show up, every day of their lives. Dr. Navaz Habib and JP Errico will bring you weekly shows including interviews with world-class experts in functional medicine, longevity, health, high performance, and functional movement. We aim to bring you game-changing tools to upgrade your performance, so you can eliminate what is holding you back, show up in your business, relationships, and family, and bring your gifts to the world. Find out more at: www.healthupgradepodcast.com Language: en Genres: Alternative Health, Health & Fitness Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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138: FoxO3 and Aging
Episode 72
Wednesday, 12 November, 2025
In this episode of the Health Upgrade podcast, we dive deep into the science behind longevity, focusing on the FOXO3 gene, a newly hot topic in genetic research for long and healthy life. Together, we break down how FOXO3 acts as a master regulator of the body’s stress response, coordinating processes like autophagy, DNA repair, and cellular protection. We also explore how the sympathetic and parasympathetic nervous systems, lifestyle factors like exercise and fasting, and even epigenetics play into FOXO3’s role in health span and aging.We make complex science approachable, sharing how brief, hormetic stressors can boost your body’s resilience, while chronic stress can burn out these protective mechanisms. Exciting new research, including breakthroughs in stem cell therapies and vagus nerve stimulation, suggests we might be on the brink of redefining what’s possible for human longevity.If you’re ready to level up your understanding of the link between genetics and healthy aging, this is an episode you won’t want to miss. Dive in, share this with a friend who’s passionate about health, and check out our previous episodes for more practical tips to support your own health upgrade journey!Dr. Navaz HabibEmail: podcast@healthupgraded.comFacebook: https://www.facebook.com/DrNavazHabib/Instagram: https://www.instagram.com/drnavazhabib/LinkedIn: https://ca.linkedin.com/in/drnavazhabibJP ErricoInstagram: https://www.instagram.com/thevnsguy/LinkedIn: https://www.linkedin.com/in/jp-errico-097629aa
