 |
Tumor Immunology Round TableYour journal club in tumor immunotherapy Author: pedro
This podcast aims to present you research articles recently published in the field of immunology and tumor immunology in an journal club format. Disclaimer: the comments provided are strictly personal and do not represent the scientific positions or scientific orientations of the institutions where the authors of this podcast work or have worked in the past. The audio soundtrack is provide by Magnatunes.com. I used the track "Innocent Murmur" from the album "First album", produced by the progressive jazz band "Thursday Group" Language: en-us Genres: Science Contact email: Get it Feed URL: Get it iTunes ID: Get it |
Listen Now...
How Alum adjuvant boost antigenic response
Monday, 21 July, 2008
In this edition, I discuss the recent paper of Kool et al submitted to JEM, and where the authors evaluate the effect of aluminum adjuvant in antigen response. The authors found thad adjuvant mix results in the mobilization of phagocytes and monocytes to the peritoneal cavity upon i.p. injection of antigen, boosting antigen specific T cell response in the draining lymph nodes The most important observation found by authors was that inflammatory monocytes mobilized by adjuvant differentiate into matured dendritic cells and such cells are key elements in the antigen T cell response. A great reading... For reference please check the mouse lymph node localizations on this link. See you soon and have a nice listening
