Ketofol Spritz

Author: Ketofol Spritz

Anaesthesia Study Notes Primary Exam Notes (OneNote) - https://1drv.ms/o/c/2894d6aaca6619c7/EscZZsqq1pQggCinAAAAAAABlhOr98uAW-U54dPADaRlXQ Final Exam Notes (OneNote) - https://1drv.ms/o/c/2894d6aaca6619c7/EscZZsqq1pQggCgSAQAAAAAB5lXsHt4li8_7JusmDWgjKw KetofolSpritz@gmail.com Link to my OneNote - scanned 1 page summaries and flashcards
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Emergencies - Fat Embolism Syndrome
Episode 1
Wednesday, 25 June, 2025

KEY POINTS:Presentation 24-72h post-injury - risk during major trauma and surgery (esp long bones)Pathophysiology:Fat from marrow into lungs = pulmonary hypertension, RV strain, hypoxiaSIRS from fatty acids = myocardial depression, ARDS, DICPrevention = early immobilisation/reduction and operative managementDx of exclusion but classic triad of GURDS = confusion, respiratory distress and petechiaePetechiae only present in 50% but pathognomonic Mx = exclude other Dx (PE, anaphylaxis) --> treat fracture (no cement)A) ETT (req in 40%)B) FiO2 1.0, ARDS-ventilationC) fluids, pressors, inotropes, coags correct (DIC)D/E) normal sugar/tempICU post-op, resolves <7 days