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The TBPodAuthor: Actnet
The TBPod is a podcast for clinicians and policymakers caring for patients with tuberculosis. The podcasts present discussions with expert clinicians, researchers, policymakers and advocates about their work in the field of tuberculosis. Tuberculosis remains one of the leading causes of death worldwide, and is an important contributor to morbidity among migrants arriving in Australia and New Zealand. There are around 1300 reported cases of TB in Australia each year, and a further 300 in New Zealand. Included in these figures are cases of multi-drug resistant (MDR) TB which pose significant barriers to treatment and management of the disease. The Australian government has committed to the global elimination of TB by 2030, but to do so requires the development of innovative new strategies, based on high-quality research, that has national and international reach. These podcasts aim to engage and update those who are interested in the field of tuberculosis through discussions with leaders in the field of tuberculosis. Language: en-us Genres: Education, Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Protecting Mothers and Infants: Dr Jyoti Mathad on TB During Pregnancy
Tuesday, 27 October, 2026
Dr Alice Sawka, adult respiratory and TB physician in Adelaide, is joined by Dr Jyoti S. Mathad, Associate Professor of Medicine and Obstetrics & Gynaecology at Weill Cornell Medicine, to discuss tuberculosis infection, prevention and treatment during pregnancy. They explore the unique immunological changes that occur during pregnancy, why pregnant women are at increased risk of developing TB disease, and the challenges of generating evidence for TB preventive treatment in this population. Dr Mathad also reflects on her work advancing the inclusion of pregnant and lactating women in TB research, the growing evidence for shorter preventive treatment regimens, and the importance of building an evidence base that improves outcomes for both mothers and their infants.Show NotesCherkos A, LaCourse S, Enquobahrie D et al. Effect of pregnancy versus postpartum maternal isoniazid preventive therapy on infant growth in HIV-exposed uninfected infants: a post-hoc analysis of the TB APPRISE trial eClinicalMedicine, 2023; 58 DOLPHIN MOMS clinicaltrials.gov listing (unpublished) https://clinicaltrials.gov/study/NCT05122026Mathad JS, Savic R, Britto P, Jayachandran P, Wiesner L, Montepiedra G, Norman J, Zhang N, Townley E, Chakhtoura N, Bradford S, Patil S, Popson S, Chipato T, Rouzier V, Langat D, Chalermchockcharoentkit A, Kamthunzi P, Gupta A, Dooley KE. Pharmacokinetics and Safety of 3 Months of Weekly Rifapentine and Isoniazid for Tuberculosis Prevention in Pregnant Women. Clin Infect Dis. 2022 May 3;74(9):1604-1613. doi: 10.1093/cid/ciab665. PMID: 34323955; PMCID: PMC9070820.
