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ASCO GuidelinesAuthor: American Society of Clinical Oncology (ASCO)
ASCO Guidelines Podcast breaks down pivotal recommendations from the latest evidence-based clinical practice guidance and provides insight into daily patient care. Listen to stay up to date with the ever-evolving landscape of cancer research and treatment. Language: en-us Genres: Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it Trailer: |
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Therapy for Stage IV NSCLC With Driver Alterations: ASCO Living Guideline Update 2026.3.2
Tuesday, 28 July, 2026
Dr. Sonam Puri joins the podcast to share the update to the living guideline on stage IV NSCLC with driver alterations. Dr. Puri discusses the practice-changing evidence reviewed for both NTRK rearrangements, including the TRIDENT-1 trial, and HER2 activating mutations, including the Beamion LUNG-1 study. She shares how these results impacted the clinical practice guideline with the addition of repotrectinib and zongertinib, what these new TKIs mean for patients, and where the panel is waiting for additional randomized data to clarify the role of therapeutic options. Dr. Puri encourages listeners to stay tuned for future updates to the living guideline as new evidence is published. Read the full living guideline "Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2026.3.2" at www.ascopubs.org/guidelines/therapy-stage-iv-non-small-cell-lung-cancer-driver-alterations" LINK TO FULL TRANSCRIPT
