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Deep brain stimulation of A13 region evokes robust locomotory response in rats
Episode 151
Wednesday, 29 October, 2025

In this episode, coauthors Anupam Bisht and Cecilia Badenhorst discuss their study, “Deep brain stimulation of A13 region evokes robust locomotory response in rats.” Their research demonstrates that deep brain stimulation (DBS) of the A13 region in rats robustly increases locomotor activity without inducing anxiety using a novel wireless stimulation approach, suggesting that A13 may be a promising therapeutic target for gait dysfunction in Parkinson’s disease. Deep brain stimulation of A13 region evokes robust locomotory response in rats Anupam Bisht, Cecilia Badenhorst, Zelma H. T. Kiss, Kartikeya Murari, and Patrick J. Whelan Journal of Neurophysiology 2025 133:5, 1594-1606