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Tierärztliche Fakultät - Digitale Hochschulschriften der LMU - Teil 03/07Language: de Genres: Education, Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Investigations into idiopathic hypertriglyceridemia in the Miniature Schnauzer in North America
Friday, 18 July, 2008
Idiopathic hypertriglyceridemia has been reported in Miniature Schnauzers. However, studies investigating the prevalence of this disorder in a large population of Miniature Schnauzers are lacking. 192 healthy Miniature Schnauzers and 38 healthy dogs of other breeds (control dogs) were enrolled in this study. Serum triglyceride and cholesterol concentrations were measured and statistically compared between the Miniature Schnauzers and the control group. Dogs were categorized based on their age, and median serum triglyceride concentrations were compared among different age groups. A total of 63 (32.8%) of the 192 Miniature Schnauzers had serum triglyceride concentrations above the upper limit of the reference range. In contrast, of the 38 control dogs, only 2 (5.3%) had serum triglyceride concentrations above the upper limit of the reference range. The median serum triglyceride concentration in Miniature Schnauzers was 73.5 mg/dL, which was significantly higher compared to that of the control group (median: 55 mg/dL; p=0.0005). Serum cholesterol concentration was above the upper limit of the reference range in 9 (9.0%) of 100 Miniature Schnauzers and in 2 (5.3%) of the control dogs. Mean serum cholesterol concentrations were not significantly different between the 2 groups (p=0.1374). Median serum triglyceride concentrations in Miniature Schnauzers increased significantly with age (p
