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The Positive Gene PodcastAuthor: Sara Kavanaugh
Welcome to The Positive Gene Podcast, where we empower those navigating hereditary cancer risks with hope and optimism. Hosted by Sara Kavanaugh, a hereditary cancer previvor living with Lynch Syndrome (MSH6) and CHEK2 genetic mutations, this show offers a unique perspective on proactive well-being. Drawing on her own experiences and work as an advocate for FORCE (Facing Our Risk of Cancer Empowered), Sara bridges the gap between scientific knowledge and the realities of life as a previvor. Through engaging discussions with experts, advocates, and fellow previvors and survivors, Sara simplifies the complexities of hereditary risk and provides insights that empower listeners to face challenges with confidence. With a background as a communications expert and storyteller, she creates a space where education meets inspiration, and science meets everyday life. Whether youre managing genetic risk, supporting a loved one, or simply curious about how genetics shape our health, this is your space to discover the transformative power of awareness and prevention. Subscribe now for a dose of empowerment in every episode. Visit www.positivegenepodcast.com to read the podcast blog, explore resources, or book Sara for your next speaking engagement! Language: en Genres: Education, Health & Fitness, Medicine, Self-Improvement Contact email: Get it Feed URL: Get it iTunes ID: Get it Trailer: |
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The Story That Changed Everything: Diane Hardesty on Lynch Syndrome, Family History, and Prevention
Episode 14
Tuesday, 31 March, 2026
As we close out Colorectal Cancer Awareness Month, this episode marks the final installment in our series on Lynch syndrome and hereditary cancer risk. If you haven’t yet, I encourage you to go back and listen to the earlier episodes—each one offers a powerful and important perspective on what it means to understand and navigate inherited cancer risk. **** Episode Overview Diane Hardesty’s story is one that clearly shows what can change when awareness meets action. Before genetic testing, Diane’s family experienced ten cancer-related deaths connected to Lynch syndrome. Cancer wasn’t a possibility, it felt inevitable. But once Diane chose to pursue genetic testing, everything shifted. Through testing, proactive screening, and open family communication, her family has now experienced zero cancer-related deaths. In this conversation, Diane shares her personal journey, the emotional weight of growing up with cancer as an expectation, and how one decision changed the trajectory for future generations. This episode is a reminder that understanding your risk doesn’t create fear—it creates options. Key Takeaways Family history matters more than many realize Patterns across generations can hold critical information about inherited cancer risk. Genetic testing can change outcomes Knowledge allows for earlier screening, prevention strategies, and informed decision-making. You are not only making decisions for yourself Testing and sharing information can directly impact children, siblings, and extended family. Prevention and early detection are powerful Diane’s family story shows what is possible when risk is understood and acted on. Conversations save lives Talking openly about cancer history within families is one of the most important steps people can take. Topics We Cover Growing up in a family where cancer felt inevitable The moment Diane first learned about Lynch syndrome Deciding to pursue genetic testing What changed after her family began testing The emotional experience of learning her son did not inherit the mutation Advocacy, awareness, and speaking on a national stage Why sharing family health history is critical How awareness continues to evolve—and where gaps still exist Resources AliveandKick’n (Lynch Syndrome advocacy and support) https://aliveandkickn.org FORCE (Facing Our Risk of Cancer Empowered) https://www.facingourrisk.org Jacqueline Rush Foundation - Lynch Syndrome Advocacy and Education https://www.jrushfoundation.org Lynch Syndrome Awareness & Education https://www.lynchsyndromeawareness.com National Society of Genetic Counselors (NSGC) – Find a genetic counselor https://www.nsgc.org NCCN Guidelines for Patients (Evidence-based screening guidance) https://www.nccn.org/patients My Faulty Gene (Advocacy + conference presence Diane supports) https://www.myfaultygene.org Final Thought Diane’s story is a powerful example of how knowledge can change a family’s future. If cancer runs in your family, or if those conversations have never happened, this episode is a place to start. 🎧 The Positive Gene Podcast - https://thepositivegenepodcast.podbean.com/ IMPORTANT: This episode is for educational purposes and is not medical advice. Always consult your healthcare team for personal guidance.













