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IHC Talk: TRBC1 in T-cell Lymphomas
Episode 7
Thursday, 20 November, 2025

The Chromogen Siblings are back to talk about TRBC1 IHC in T-cell Lymphomas! Dr. Mike Arnold (@MArnold_PedPath),  Dr. Andrew Bellizzi (@IHC_guy), and Dr. Sanam Loghavi (@sanamloghavi) speak with Dr. Pranav Patwardhan and Dr. Erika Moore of the University of Pittsburgh Medical Center about their publication in the American Journal of Surgical Pathology: The Utility of TRBC1 Immunohistochemistry in the Evaluation of T-Cell Lymphomas.  Hear about the Hematopathology practice in different institutions, and the challenges in diagnosing T-cell lymphomas. We also hear about how Hematopathologists can use TRBC1 IHC to identify clonal populations of T-cells to support the diagnosis of T-cell lymphoma.   Featured article:  The Utility of TRBC1 Immunohistochemistry in the Evaluation of T-Cell Lymphomas https://journals.lww.com/ajsp/abstract/9900/the_utility_of_trbc1_immunohistochemistry_in_the.563.aspx   Featured public domain music: Alpha Hydrae, Won't see it comin'

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