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One Thing with Dr. Adam RindeAuthor: Dr. Adam Rinde
The most engaging conversation between health professionals happens in chance meetings in the hallways. During these moments so much is learned .*One Thing* brings together thought leaders in conversation and we share it with health enthusiasts , practitioners, and learners. Our conversations primarily focus on one significant thing in the arenas of gut health, brain health, immune system, metabolism, performance, and aging . This for clinicians and patients alike who are insightful and motivated. find us on Listen Notes Language: en Genres: Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Episode 131: What If Inflammation Could Be Removed? Therapeutic Plasma Exchange with Dr. Pamela Smith
Episode 131
Sunday, 15 February, 2026
What if inflammation isn’t just something to manage… but something you could actually remove?For decades, chronic inflammation has been treated with suppression — steroids, biologics, immune blockers. But what if there were a way to physically remove inflammatory burden from the bloodstream?In this episode, we sit down with Dr. Pamela Smith — ER physician, toxicologist, hormone specialist, and pioneer in therapeutic plasma exchange (TPE) — to explore the emerging science behind physically reducing inflammatory load.We break down:• What actually happens during therapeutic plasma exchange• How inflammation, cytokines, and antigen load circulate in the blood• Why autoimmune disease may be driven by persistent toxin burden• The connection between mold, plastics, metals, and immune dysfunction• Whether TPE can help long COVID, PCOS, cardiovascular disease, and cognitive decline• Who should — and shouldn’t — consider this therapyThis is not a hype episode.It’s a grounded, nuanced exploration of what’s possible when inflammation is treated as something measurable — and potentially removable.If you’re navigating autoimmune disease, chronic illness, hormone resistance, long COVID, or simply want to understand the future of inflammation science, this conversation will challenge how you think about immune regulation.Is therapeutic plasma exchange the next frontier in functional medicine — or an emerging tool still finding its evidence base?Let’s explore the science.













