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Beyond the AbstractAuthor: Beyond the Abstract
Hey science nerds! Welcome to Beyond the Abstract, a science podcast dedicated to discussion of the coolest cutting edge, basic science research papers in a way that just about anyone can understand. We're your hosts, Derek, Dan, and Ellen, three MD/PhD students coming from the University of Pennsylvania and Harvard Medical School who are passionate about science communication and bridging the gap between science and medicine. In each episode, well dive into a paper and talk about the experiments these scientists did, what it means for the future of research, and even potential impacts on human health and medicine. We've invited experts in these fields to help us understand and dissect these complicated but impactful papers. We can't wait to share all this cool science with you. Disclaimer: This podcast is for informational purposes only and NOT intended as medical advice. The views and opinions expressed are those of the hosts and guests and do not reflect the University of Pennsylvania. Business contact: beyondabstractpod@gmail.com Language: en Genres: Education, Life Sciences, Science Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Blood Biopsies: Novel Screening for Cancer and Beyond
Wednesday, 30 April, 2025
Cancer is notoriously challenging to detect early, which is a significant problem as early cancer detection saves lives. While there are many approaches to detect cancer early, too many cancers are detected too late. In today's episode of Beyond the Abstract, Derek and Dan discuss an important new approach to cancer detection called a blood biopsy, which analyses molecules in a blood draw to search for signs of cancer. They discuss a new study using blood biopsies to detect colon cancer, and explain some statistical principles that help us understand whether a new cancer test actually works.Articles discussedA Cell-free DNA Blood-based Test for Colorectal Cancer Screening. Chung et al. 2024 NEJM. ECLIPSE trialNext-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening. Imperiale et al. 2024 NEJM. BLUE-C trial
