Performance Around The Clock

Author: Dr. Satchin Panda

This is a podcast that explores how to keep our bodies and minds operating at peak levels around the clock, hosted by Dr. Satchin Panda from the Salk Institute in La Jolla, CA. Here, we talk with experts from different fields to learn about science and how to leverage that knowledge to improve performance. Dr. Panda is a leading expert on circadian rhythms and time-restricted feeding. His research has implications on metabolism, health, and aging and offers potential approaches to disease prevention and longevity.
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Language: en

Genres: Life Sciences, Science

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Emily Manoogian - optimizing shift work health. Performance Around the Clock episode 40.
Thursday, 29 January, 2026

In episode 40 of the Performance Around The Clock podcast, we are joined by Dr. Emily Manoogian, a leading clinical researcher focused on optimizing human health through the timing of food intake (time-restricted eating) and circadian rhythm regulation. Dr. Manoogian was recently honored with the Young Investigator Award for her seminal studies on circadian disruption among shift workers and interventions to mitigate its effects. We begin the episode by defining the complex reality of shift work—whether fixed, rotating, or split shifts—and how working outside typical hours challenges the human body.Dr. Manoogian and Panda explore the cascading health effects of "circadian disruption," distinguishing between acute annoyances and chronic risks that build up over months and years. Dr. Manoogian explains how being active and eating when the body expects rest can lead to insulin resistance, cardiovascular disease, mood disorders, and even increased cancer risk. We also discuss the broader societal impacts, from the "social jetlag" affecting students and new parents to the unique stressors faced by frontline workers like firefighters and nurses.The conversation highlights actionable science, focusing on the "Healthy Heroes" study conducted with San Diego firefighters. Dr. Manoogian shares how Time-Restricted Eating (TRE)—limiting food intake to a 10-hour window—significantly reduced VLDL (bad cholesterol). reduced blood sugar levels, improved blood pressure and improved emotional stability in this high-stress population. Dr. Manoogian is currently studying a different shift work group with the ongoing "Shift Study" for nurses, which is using continuous glucose monitoring to test if optimizing meal timing and low-glycemic snacks can protect the cardiometabolic health of night-shift workers.Please join us for this vital discussion on optimizing health for those who keep our society running around the clock. If you enjoy this episode, please like, comment, or follow. Thanks for listening.Guest:Dr. Emily ManoogianHillblom Fellow, Staff Scientist at the Salk Institute for Biological StudiesYoung Investigator Award Winner, Working Time SocietymyCircadianClock website:www.mycircadianclock.orgHealthy HEROES study:https://pmc.ncbi.nlm.nih.gov/articles/PMC9536325/SHIFT study:Participate by emailing:research@mycircadianclock.orgHost:Dr. Satchin PandaX (Twitter): @SatchinPandahttps://x.com/SatchinPandaInstagram: @satchin.pandahttps://www.instagram.com/satchin.panda/Links:Donations: https://panda.salk.edu/giving/Research: https://www.salk.edu/scientist/satchidananda-panda/More science: ⁠https://mycircadianclock.org/⁠