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Performance Around The ClockAuthor: Dr. Satchin Panda
This is a podcast that explores how to keep our bodies and minds operating at peak levels around the clock, hosted by Dr. Satchin Panda from the Salk Institute in La Jolla, CA. Here, we talk with experts from different fields to learn about science and how to leverage that knowledge to improve performance. Dr. Panda is a leading expert on circadian rhythms and time-restricted feeding. His research has implications on metabolism, health, and aging and offers potential approaches to disease prevention and longevity. Language: en Genres: Life Sciences, Science Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Anna Krook - exercise timing. Performance Around the Clock episode 37
Episode 31
Monday, 27 October, 2025
Episode 37 of the Performance Around the Clock comes from the XVIII Congress of the European Biological Rhythms Society in Lubeck, Germany. We welcome Professor Anna Krook, a Professor of Integrative Physiology at the Department of Physiology and Pharmacology and chair of the Strategic Research Programme in Diabetes at Karolinska Institutet. Professor Krook is an internationally recognized leader in metabolism, skeletal muscle and insulin biology. In this episode, we discuss Professor Krook’s research journey, which began with her Ph.D. work on insulin and the insulin receptor gene, identifying rare mutations that cause severe inherited insulin resistance. She then focused on the dysregulation of insulin action seen in Type 2 diabetes, noting that muscle is the main site where insulin action goes wrong. The conversation dives into the fascinating role of the circadian clock in regulating insulin, glucose, and muscle. Dr. Krook explains that while healthy muscle mitochondria show a functional rhythm that peaks in the afternoon, this crucial rhythm is absent in muscle cells from people with Type 2 diabetes. We cover her landmark study showing that for type 2 diabetic men doing high-intensity interval training, exercise in the afternoon led to lower blood glucose control and a beneficial "legacy effect" the next day. In contrast, morning exercise resulted in higher blood glucose levels for that entire day and the next. This negative effect may be linked to higher inflammatory markers and stress markers circulating in the plasma after morning exercise. Please join us for an insightful conversation between Dr. Satchin Panda and Dr. Krook on optimizing exercise timing for metabolic health. If you enjoy this episode, please like, comment or follow. Thanks for listening.Guest:Dr. Anna KrookKarolinska InstitutetProfessor of Integrative PhysiologyChair of the Strategic Research Programme in DiabetesProfile:https://ki.se/en/people/anna-krookIntegrative Physiology group:https://ki.se/en/fyfa/integrative-physiologyPaper highlight:Afternoon exercise is more efficacious than morning exercise at improving blood glucose levels in individuals with type 2 diabetes: a randomised crossover trialhttps://pubmed.ncbi.nlm.nih.gov/30426166/Host:Dr. Satchin PandaX (Twitter): @SatchinPandahttps://x.com/SatchinPandaInstagram: @satchin.pandahttps://www.instagram.com/satchin.panda/Links:Donations: https://panda.salk.edu/giving/Research: https://www.salk.edu/scientist/satchidananda-panda/More science: https://mycircadianclock.org/
