 |
The Big4Bio PodcastThe Big4Bio Podcast shares podcasts that give ins Author: Big4Bio
The Big4Bio Podcast shares podcasts that give insight and information about/from biotech and life science leaders and organizations within the Big4Bio regions. Check out our Playlists to hear podcasts by region. Language: en Genres: Science Contact email: Get it Feed URL: Get it iTunes ID: Get it |
Listen Now...
Every Moment Matters: Getting Better Insights on Target and off Target Biology
Wednesday, 21 January, 2026
Biologic drug development increasingly relies on sensitive, human relevant platforms capable of detecting both intended and unintended target engagement well before first in human studies. Charles River Laboratories is leveraging its Retrogenix cell microarray platform alongside traditional tissue cross-reactivity studies to gain a more comprehensive view of target and off-target biology. We spoke with Charles River Labs Associate Director of Advanced Modalities Mark Aspinall O’Dea and Charles River Labs Senior Scientific Director James Raymond, about how combining these two approaches helps sponsors select better leads, design safer studies, and meet regulatory expectations for complex modalities.
