eanCast: Weekly Neurology

Author: ean.org

Official neurology podcast of the European Academy of Neurology (EAN). Expert talks on general neurology, stroke, dementia, epilepsy & many more. New episodes every Monday. For neurology residents, clinicians & researchers. A resource for continuing medical education and lifelong learning.
Be a guest on this podcast

Language: en

Genres: Health & Fitness, Medicine, Natural Sciences, Science

Contact email: Get it

Feed URL: Get it

iTunes ID: Get it

Get all podcast data

Listen Now...

Ep. 189: Red flags of treatable (spino)cerebellar ataxias
Sunday, 22 February, 2026

Moderator: João Durães (Coimbra, Portugal) Guests: Paola Giunti (London, UK), Lidia Sarro (Milan, Italy) In this episode, João Durães, Paola Giunti and Lidia Sarro provide a rigorous examination of the diagnostic and therapeutic landscape of treatable ataxias, focusing on rare variants. The discussion first delineates autoimmune etiologies, such as anti-GAD, paraneoplastic, and gluten-related syndromes, before transitioning to a detailed review of acquired and genetic metabolic disorders, including vitamin deficiencies, NPC, Refsum disease, Glut1 deficiency, CTX, and Wilson’s disease among others. By highlighting critical clinical and paraclinical "red flags," the contributors offer a framework for accelerating differential diagnosis. The session concludes with an analysis of contemporary pharmacological advancements, notably the recent EMA approval for Friedreich’s Ataxia and the efficacy of repurposed drugs in treating genetic forms such as EA1/2 and SCA27B.