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GES Center Lectures, NC State UniversityGenetic Engineering & Society Center Where biotechnology meets societyethics, policy, and practice. Author: Patti Mulligan
Recorded live from NC States GES Colloquium, this show explores how biotechnologies move from lab to life: microbiome engineering in buildings, CRISPR in agriculture and forestry, gene drives and integrated pest management, data governance and benefit-sharing, risk analysis and regulation, sci-art collaborations, and practical models of responsible innovation and public engagement. Episodes feature researchers, students, and community partners in candid conversations about decisions, trade-offs, and impacts. Learn more at go.ncsu.edu/ges and sign up for our newsletter at http://eepurl.com/c-PD_T. Produced by Patti Mulligan, Communications Director, GES Center, NC State Language: en-us Genres: Courses, Education, Natural Sciences, Science Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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S13E1 - Catching Up on the CRISPR Craze with Rodolphe Barrangou
Episode 1
Wednesday, 21 January, 2026
Recorded from NC State’s GES Colloquium, this podcast examines how biotechnologies take shape in the world: microbiome engineering in built environments, gene editing and gene drives, forest and agricultural genomics, data governance and equity, risk and regulation, sci-art, and public engagement in practice. _________ Catching up with the CRISPR Craze Nelson 4305 + Zoom | Deploying and commercializing genome editing technologies: challenges, opportunities, and implications of disruptive technologies The advent of CRISPR-based technologies has revolutionized our ability to manipulate the genetic content of organisms across the tree of life and democratized genome editing across the globe. Repurposed from obscure adaptive immune systems in bacteria, CRISPR molecular machines have been broadly deployed in academia and industry in the past 10 years to manipulate the genomes of organisms relevant to medicine, biotechnology, and agriculture. We now have access to a portable CRISPR toolbox enabling flexible editing from a single nucleotide to large-scale genome manipulation in organisms that span minimalistic viruses to large trees and their corresponding genome range and complexities. So far, most applications focus on the design of efficacious and safe gene and cell therapies to address human disease. Yet, there are un(der)-appreciated opportunities to deploy genome editing modalities for sustainable agriculture, to enhance crops (yield and traits), but also livestock, trees, and organisms used throughout the food supply chain. There is a path to next-generation therapies by 2030, sustainable agriculture by 2040, and breeding healthier forests by 2050. Besides the technical bottlenecks, it is also necessary to account for regulatory frameworks, intellectual property pursuit, public engagement, ethical deployment, consumer acceptance, and geopolitical issues impacting our practical ability to harness genome editing to address medical, agricultural, and environmental challenges that require such disruptive technologies. Related links: CRISPR Lab – Publications CRISPR Lab – Research Download seminar poster Rodolphe Barrangou, PhD Distinguished Professor at NC State University | Profile Rodolphe Barrangou, Ph.D., is the Todd R. Klaenhammer Distinguished Professor at North Carolina State University. Rodolphe spent 9 years in R&D and M&A at Danisco and DuPont, and has been at NC State since 2013. For his CRISPR work, Rodolphe received several international awards, including the 2016 Canada Gairdner International Award, the 2016 Harvard Medical School Warren Alpert Prize, the 2017 NAS Award in Molecular Biology, and the 2018 NAS Prize in Food and Agriculture Sciences. He has been elected into the National Academy of Sciences, the National Academy of Engineering, the National Academy of Inventors, the American Academy of Arts and Sciences, and the National Inventors Hall of Fame. Dr. Barrangou earned a BS in Biological Sciences from Rene Descartes University, France, an MS in Biological Engineering from the University of Technology in Compiegne, France, an MS in Food Science from NC State, a PhD in Genomics from NC State, and an MBA from the University of Wisconsin-Madison. Dr. Barrangou is also the former Chairman of the Board of Caribou Biosciences (NASDAQ CRBU), a co-founder of Intellia Therapeutics (NASDAQ NTLA), Locus Biosciences, TreeCo, Ancilia Biosciences, and CRISPR Biotechnologies, an advisor to Inari Ag, Provaxus, the KiTua fund, and the Editor in Chief of the CRISPR Journal. At NC State, Professor Barrangou holds appointments and affiliations in a dozen departments, academic programs, and centers, supporting the land-grant mission of the University. __________ The Genetic Engineering and Society (GES) Colloquium is a seminar series that brings in speakers to present and stimulate discussion on a variety of topics related to existing and proposed biotechnologies and their place within broader societal changes. GES Colloquium is taught by Dr. Zack Brown, and the seminars serve as a great opportunity for our students to build their networks and grow as professionals. To support their efforts, we encourage you to join our in-person seminars, which will now take place in Nelson 4305. Please subscribe to the GES newsletter and LinkedIn for updates. Genetic Engineering and Society Center Colloquium Home | Zoom Registration | Watch Colloquium Videos | LinkedIn | Newsletter GES Center at NC State University—Integrating scientific knowledge & diverse public values in shaping the futures of biotechnology. Produced by Patti Mulligan, Communications Director, GES Center, NC State Find out more at https://ges-center-lectures-ncsu.pinecast.co
