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Lab Rats to Unicorns  

Lab Rats to Unicorns

LRTU

Author: John Flavin

Lab Rats to Unicorns is a podcast that aims to demystify the process of creating a great company in life sciences. Under the guidance of our host, John Flavin, you will hear personal stories of creation, be able to understand how great companies are created, and get insights into the many ways that you as an individual can engage in the creation of tomorrows life science companies. From the lab rat, signifying the process of invention and discovery, to the unicorn, signifying market success, there are a thousand players and ways in which people can contribute to the creation of great companies.
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Language: en

Genres: Business, Entrepreneurship, Life Sciences, Science

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Chasing the Holy Grail of Transplantation with Dr. Joseph Leventhal_e.076
Episode 76
Wednesday, 19 November, 2025

In this episode of Lab Rats to Unicorns, John Flavin sits down with Dr. Joseph Leventhal, Professor of Surgery and Director of Living Donor Kidney Transplantation at Northwestern University Feinberg School of Medicine. A pioneer in the field of organ transplantation, Dr. Leventhal’s research is redefining what’s possible in immune tolerance—an area often described as the “holy grail” of transplantation, where a patient’s body can accept a donated organ without lifelong immunosuppressive drugs.Dr. Leventhal shares his journey from growing up in New York City to becoming one of the foremost leaders in transplant surgery and cell therapy innovation. He discusses how his team’s groundbreaking clinical work has shown that tolerance can be achieved through cellular therapies, potentially freeing patients from the burdens of chronic immunosuppression.From the early days of cyclosporine to founding TRACT Therapeutics and developing first-in-human T-regulatory cell therapies, Joe reflects on the scientific curiosity, resilience, and collaboration that drive progress in a complex field. He also explores the evolving ecosystem for biotech innovation in Chicago, the challenges of translating academic research into clinical therapies, and the optimism surrounding the next generation of precision cell therapies.

 

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