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Armchair Expert with Dax ShepardAuthor: Armchair Umbrella
Hi, Im Dax Shepard, and I love talking to people. I am endlessly fascinated by the messiness of being human, and I find people who are vulnerable and honest about their struggles and shortcomings to be incredibly sexy. I invite you to join me as I explore other peoples stories. We will celebrate, above all, the challenges and setbacks that ultimately lead to growth and betterment. What qualifies me for such an endeavor? More than a decade of sobriety, a degree in Anthropology and four years of improv training. I will attempt to discover human truths without any laboratory work, clinical trials or data collection. I will be, in the great tradition of 16th-century scientists, an Armchair Expert.Follow Armchair Expert on the Wondery App or wherever you get your podcasts. Watch new content on YouTube or listen to Armchair Expert early and ad-free by joining Wondery in the Wondery App, Apple Podcasts, or Spotify. Start your free trial by visiting wondery.com/links/armchair-expert-with-dax-shepard/ now. Language: en Contact email: Get it Feed URL: Get it iTunes ID: Get it Trailer: |
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Colleen Cutcliffe (on the microbiome)
Episode 1012
Wednesday, 18 February, 2026
Colleen Cutcliffe (Pendulum Therapeutics) is a doctor of biochemistry and microbiology and CEO and co-founder of Pendulum Therapeutics. Colleen joins the Armchair Expert to discuss starting a microbiome supplement company inspired by her premature daughter who had to take antibiotics, applying hyenas' evolved ability to digest rotting meat to study gut bacteria, and how fecal transplants reliably help treat C. diff. Colleen and Dax talk about the real linkages between microbiome and depression, obesity, and more, how the body’s natural GLP1s function, and why a healthy gut is a resilient gut. Colleen explains her wooden fence analogy to illustrate leaky guy syndrome, remarkable results from experiments giving mice Akkermansia, and that the beauty of the microbiome is that everything is recoverable.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
