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Biomedical Frontiers: Stories with Innovators in HealthcareAuthor: Dasha Tyshlek
Welcome to 'Biomedical Frontiers: Stories with Innovators in Healthcare,' a podcast produced by the University of Virginia's Wallace H. Coulter Center for Translational Research.Biomedical Frontiers is a forum for in-depth discussions at the intersection of healthcare technology and translational research. We feature leading voices from the University of Virginia community and the broader biomedical industry. Each episode explores pivotal research projects and disruptive innovations aimed at translating scientific advancements into tangible healthcare solutions. Rooted in the Coulter Center's mission, this podcast seeks to dissect the methodologies and implications of explicitly translational research, examining their potential to reshape medical practice and patient outcomes.Join us on this intellectual voyage, where we unravel the complexity of biomedical innovation, fostering a deeper understanding of its impact on healthcare and the broader scientific community. Notable guests of the podcast include Dr. Nathan Price, Chief Science Officer of Thorne Health and co-author of The Age of Scientific Wellness: Why the Future of Medicine is Personalized, Predictive, Data Rich and in Your Hands, Dr. Natasha Sheybani, a pioneering researcher in Focused Ultrasound Immunotherapy and the winner of Forbes 30 under 30 in Science, and Dr. Jennifer West, University of Virginias Dean of the School of Engineering.-----------------Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.comExecutive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVA Coulter CenterSenior Producer: Hannah Moore, Associate Director, UVA Coulter CenterDesign Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com---------------------Produced by the Wallace H. Coulter Center for Translational Research at University of Virginia.https://www.engineering.virginia.edu/centers-institutes/coulter-center-translational-research Language: en Genres: Health & Fitness, Life Sciences, Medicine, Science Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Crossing the Valley of Death: How the Manning Institute Will Transform Science into Medicines
Episode 20
Wednesday, 21 January, 2026
Why do so many promising scientific discoveries never become real medicines?In this episode of Biomedical Frontiers Dr. Mark Esser, Chief Scientific Officer of the Paul and Diane Manning Institute of Biotechnology at the University of Virginia, describes one of the biggest challenges in healthcare innovation: the translational valley of death.Dr. Esser explains how the Manning Institute is being built to bridge the gap between academic discovery and patient-ready therapies. Drawing on decades of experience in industry, he shares how infrastructure, cross-disciplinary teams, regulatory expertise, and new funding models are essential to turning science into medicine.The conversation explores:Why promising biomedical research often stalls before reaching patientsHow the Manning Institute’s Accelerate, Create, Educate (ACE) model is designed to overcome these barriersA real-world case study of a novel sepsis therapy entering clinical trialsWhat this effort means for the future of drug discovery and Virginia’s growing biotech ecosystemFollow Dr. Mark Esser on Social MediaLinkedIn: https://www.linkedin.com/in/mark-esser-0b152b2/Email: mark.esser@virginia.eduPaul and Diane Manning Institute of Biotechnology (University of Virginia) https://manninginstitute.virginia.eduUVA Licensing & Ventures https://lvg.virginia.edu/Resources:Recommended Book: “A Practical Guide to Drug Development in Academia” https://catalog.nlm.nih.gov/permalink/01NLM_INST/vdtut1/alma9916234173406676SPARK Drug Discovery Model (Stanford) https://sparkmed.stanford.eduLove this episode? Follow and write to us: 📸 Instagram: @biomedicalfrontiers 🔗 LinkedIn: https://www.linkedin.com/company/uvacoulter 📧 Reach us: biomedicalfrontiers@virginia.eduDirector & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.comExecutive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVASenior Producer: Hannah Moore, Associate Director, UVA CoulterDesign Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.comProduced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research
