BREAKING THROUGH with Madeline Bell Author: Childrens Hospital of Philadelphia Madeline Bell, CEO of the renowned Childrens Hospital of Philadelphia, takes you behind the scenes to meet the brilliant minds who are making - and supporting - incredible breakthroughs in pediatric medicine. Be a guest on this podcast Language: en Genres: Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it Trailer: Get all podcast data

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Advancing Gene Therapy: Personalized Gene Editing
Episode 23
Monday, 13 October, 2025

When baby KJ was diagnosed with a rare metabolic disorder, the team at Children’s Hospital of Philadelphia (CHOP) had a unique treatment option for him: a personalized gene editing therapy developed in collaboration with Penn Medicine. On this episode, Madeline speaks to CHOP geneticist Dr. Rebecca Ahrens-Nicklas, who describes how KJ’s first-of-its-kind treatment was developed – and what this amazing breakthrough means for other patients. 

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