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Thinking About Ob/GynAuthor: Antonia Roberts and Howard Herrell
A fresh and evidence-based perspective of all things related to obstetrics and gynecology. Follow us on Instagram @thinkingaboutobgyn or visit thinkingaboutobgyn.com for show notes and more. Language: en-us Genres: Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Episode 11.8 MTHFR, Bed Rest, and More!
Episode 8
Wednesday, 15 April, 2026
We take on four stubborn myths in modern obstetrics and follow the evidence instead of the vibes, from thrombophilia testing to bed rest to seizure prophylaxis. We also spotlight a patient-empowering insulin strategy that may improve gestational diabetes outcomes faster than usual care. • distinguishing recurrent pregnancy loss evaluation from venous thromboembolism testing • focusing thrombophilia workups on antiphospholipid antibody syndrome when criteria are met • explaining why MTHFR variants and PAI-1 polymorphisms do not belong in routine panels • unpacking how social media and narrative fallacies keep low-value tests alive • reviewing the AWARE trial and why activity restriction lacks benefit and carries harms • clarifying reasonable pregnancy activity modifications versus false labor prevention claims • assessing late preterm antenatal corticosteroids for twins and the hypoglycemia signal • discussing inertia of practice and why weak evidence becomes hard to undo • breaking down patient-led insulin titration for gestational diabetes and why it may reduce macrosomia • evaluating laboring down and long-term pelvic floor outcomes plus statistical pitfalls • answering a listener question on Keppra alternatives to magnesium for preeclampsia seizures Be sure to check out thinking about obgyn.com for more information, and be sure to follow us on Instagram.0:00 Welcome And What We’re Reviewing0:28 Thrombophilia Testing After Miscarriage3:51 What Belongs In A VTE Panel5:55 MTHFR And PAI1 Myth Busting13:36 Activity Restriction And The AWARE Trial23:27 Practical Counseling Without False Promises27:08 Late Preterm Steroids For Twins32:53 Patient-Led Insulin Titration In GDM38:38 Laboring Down And Pelvic Floor Outcomes47:51 Keppra Versus Magnesium For Preeclampsia1:00:25 Wrap Up And Where To FollowFollow us on Instagram @thinkingaboutobgyn.
