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Tech Talks DailyAuthor: Neil C. Hughes
If every company is now a tech company and digital transformation is a journey rather than a destination, how do you keep up with the relentless pace of technological change? Every day, Tech Talks Daily brings you insights from the brightest minds in tech, business, and innovation, breaking down complex ideas into clear, actionable takeaways. Hosted by Neil C. Hughes, Tech Talks Daily explores how emerging technologies such as AI, cybersecurity, cloud computing, fintech, quantum computing, Web3, and more are shaping industries and solving real-world challenges in modern businesses. Through candid conversations with industry leaders, CEOs, Fortune 500 executives, startup founders, and even the occasional celebrity, Tech Talks Daily uncovers the trends driving digital transformation and the strategies behind successful tech adoption. But this isn't just about buzzwords. We go beyond the hype to demystify the biggest tech trends and determine their real-world impact. From cybersecurity and blockchain to AI sovereignty, robotics, and post-quantum cryptography, we explore the measurable difference these innovations can make. Whether improving security, enhancing customer experiences, or driving business growth, we also investigate the ROI of cutting-edge tech projects, asking the tough questions about what works, what doesn't, and how businesses can maximize their investments. Whether you're a business leader, IT professional, or simply curious about technology's role in our lives, you'll find engaging discussions that challenge perspectives, share diverse viewpoints, and spark new ideas. New episodes are released daily, 365 days a year, breaking down complex ideas into clear, actionable takeaways around technology and the future of business. Language: en Genres: News, Tech News, Technology Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Could Disease Chemistry Help Treat the Brain With Enabled Therapeutics
Episode 3682
Thursday, 13 August, 2026
What if the chemistry created by neurological disease could help activate medicine precisely where it is needed? In this episode of Tech Talks Daily, I speak with Sara Isbell, neuroscientist and co-founder of Enabled Therapeutics, about a proposed approach to one of medicine's most stubborn problems: delivering effective drugs to diseased brain tissue without exposing healthy areas to the same activity. Sara explains how the blood-brain barrier prevents many promising compounds from reaching the brain. When drugs do enter, they may spread across healthy and diseased regions alike, creating a difficult balance between therapeutic benefit and unwanted effects. We hear how an unexpected laboratory result led Sara and her co-founder to investigate whether pathological oxidative stress could convert a precursor molecule into a biologically active compound near the affected tissue. Sara describes this as pathology-gated therapeutic activation, where disease-associated chemistry provides the trigger that turns the medicine on. This remains developing science. At the time of recording, Enabled Therapeutics was preparing its first peer-reviewed manuscript and seeking partners to support further studies. Sara explains why reproducible evidence, regulatory guidance, and careful laboratory validation must determine whether the hypothesis advances. We also discuss how AI helps small biotechnology teams review literature, organize regulatory materials, connect ideas across scientific disciplines, and identify possible hypotheses. However, Sara offers an important reminder: AI can propose possibilities, but nature and experimental evidence decide what is true. Could following one unexpected result eventually offer researchers another way to approach neurological disease? Listen to the conversation and share your thoughts with me.
