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The Endometriosis PodcastAuthor: Nicholas Fogelson and Shanti Mohling
The Endometriosis Podcast is a monthly discussion of what's new in the world of endometriosis research, new discoveries, surgical techniques, and anything else of interest in the endometriosis world. Hosted by Nicholas Fogelson, MD and Shanti Mohling, MD of Northwest Endometriosis and Pelvic Surgery. For clinical consultation, call Northwest Endometriosis and Pelvic Surgery in Portland, OR at 503-715-1377 or email: newpatients@nwendometriosis.com Language: en Genres: Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Could GLP-1s Shape the Future of Endometriosis Care?
Episode 15
Thursday, 2 July, 2026
In this episode, Dr. Shanti Mohling and Dr. Nicholas Fogelson explore one of the most intriguing emerging questions in endometriosis care: could GLP-1 receptor agonists, such as Ozempic and Zepbound, play a role in reducing endometriosis-related symptoms? These medications are not currently FDA-approved for endometriosis, and the evidence is still early. But patient reports, survey data, and basic science raise compelling questions about how GLP-1s may affect inflammation, pain, and the broader systemic nature of endometriosis. Drs. Fogelson and Mohling discuss what is known, what remains speculative, the potential risks, and why a possible non-hormonal approach is worth watching. Highlights: How GLP-1 receptor agonists work beyond blood sugar and weight, including effects on appetite, satiety, reward pathways, the microbiome, and inflammation. Why endometriosis is increasingly understood as a systemic inflammatory disease, not just lesions in the pelvis. Early observations from patients and surveys suggesting some people with endometriosis report symptom improvement while taking GLP-1 medications. The current limits of the evidence, including the lack of randomized trials and the fact that GLP-1s are not medically indicated for endometriosis. Potential risks and side effects, including gastrointestinal symptoms, gastroparesis, gallbladder disease, pancreatitis, muscle loss, and the need for medical supervision. NOTE: Anyone considering GLP-1s should speak with their own physician about potential risks, side effects, and whether they are appropriate. For clinical consultations: contact Northwest Endometriosis and Pelvic Surgery in Portland, OR at (503) 715-1377 or email us at newpatients@nwendometriosis.com Follow us on Instagram: @Nicholasfogelson and @drshantimohling Download a transcript of this episode.
