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AudiommunityAuthor: Audiommunity.org
A podcast about our bodies' never-ending fight with the outside world Language: en Genres: Health & Fitness, Medicine, Science Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Episode 54 - Poop is lumen
Episode 54
Tuesday, 7 April, 2026
In this episode, Matt and Kevin discuss a new paper showing a new technique to add poly-A tails to every RNA in a tissue section, enabling capture by spot-based sequencing technologies. This let’s them see microbes and host-encoded non-messenger RNAs, giving a much better view into intestinal biology.Plus, Matt thinks it’s funny they’re taking tissue slices though fecal pellets and Kevin routinely says “microvillus” when he means “villus”, and pretends to know the anatomy of the intestines when he clearly doesn’t, despite being an Assistant Professor in the GI division at a hospital.Links* The paper - Spatial transcriptomics maps host–gut microbiome biogeography at high resolution* The technologies - 10x Visium, StereoSeq, and CosMx* Wikipedia - human digestive system Get full access to Audiommunity Org at audiommunity.substack.com/subscribe
