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The Empowering Neurologist PodcastAuthor: David Perlmutter
The Empowering Neurologist is an interview series with some of the most exciting thought leaders in the field of health and wellness. Language: en-us Genres: Health & Fitness, Medicine Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Why You Feel Older Than Your Labs Say You Are with Dr. Will Cole | E224
Tuesday, 1 September, 2026
🧠Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr.Perlmutter’s newsletter at: www.drperlmutter.com. ✉ 🌱 Thank you to our sponsors:EVY - https://www.optoceutics.com/perlmutter and the code perlmutter26 will be auto-applied to your order to get 10% off & free shipping (90 days risk-free).3x4 Genetics - https://3x4genetics.com/DrPerlmutter for a special offer when you sign up to decode your genetics and get personalized, science-backed health recommendations.====Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available! Discover how to protect your brain and future health - grab your copy today at https:/www.braindefenders.com.====Why do some people feel exhausted, mentally foggy, metabolically unwell, or simply older than they should even when their routine laboratory results are considered “normal”?That question is at the heart of this episode of The Empowering Neurologist, featuring functional medicine practitioner Dr. Will Cole, coauthor with Dr. Josh Axe of Heal Your Cells: Reversing the Irreversible.Dr. Cole and Dr. Perlmutter explore the idea that long before disease becomes obvious, dysfunction may already be developing at the cellular level. This concept takes on particular importance when we consider the brain, which accounts for only about 2% of body weight but consumes roughly 20% of the body's energy at rest.The conversation examines how seemingly separate factors including metabolic dysfunction, chronic inflammation, poor sleep, environmental exposures, physical inactivity, and prolonged psychological stress can converge on the same cellular systems and ultimately influence brain health.00:00 — Why Your Cells May Be Aging Before You Feel It03:44 — Meet Dr. Will Cole04:50 — What Is Cellular Dysfunction?09:25 — Why Healthy People Can Still Develop Disease10:32 — The Environmental Factors Affecting Cellular Health15:47 — Why Mitochondria Are Central to Health16:37 — How Mitochondrial Dysfunction Drives Inflammation19:57 — How Much of Aging Can We Actually Change?20:47 — The Connection Between Mitochondria and Insulin Resistance25:43 — Mitochondria, Microglia, and Brain Inflammation29:28 — Why There Is No One-Size-Fits-All Diet32:03 — Training Your Cells to Become More Resilient32:46 — What Are “Adversity Mimetics”?35:51 — Why Intracellular Health Matters36:32 — Why Conventional Medicine May Be Missing Cellular Dysfunction37:58 — What Do We Really Know About Peptides?40:16 — Is Ozone Therapy Worth Considering?42:30 — Ozone and the Science of Cellular Resilience43:41 — What Is Therapeutic Plasma Exchange?45:38 — Who Might Benefit From Plasma Exchange?46:45 — The Everyday Habits That Support Cellular Health51:35 — Your Cells Are Responding to the Choices You MakeDr. Will Cole is a leading functional medicine expert specializing in thyroid health, autoimmune conditions, hormonal imbalances, digestive disorders, and brain health. He is the host of The Art of Being Well podcast and a New York Times bestselling author of Intuitive Fasting, Ketotarian, The Inflammation Spectrum, and Gut Feelings.- - - - -Connect with Dr. Will ColeWebsite: https://drwillcole.comInstagram: https://www.instagram.com/drwillcoleLinkedIn: https://www.linkedin.com/in/drwillcoleFacebook: https://www.facebook.com/doctorwillcolePodcast: https://open.spotify.com/show/6z1lJ5dfKNHwGGQPOFTc7EApple Podcasts: https://podcasts.apple.com/us/podcast/the-art-of-being-well/id1539535133- - - - -Connect with Dr. David Perlmutter, MDWebsite: https://www.drperlmutter.com/Instagram: https://www.instagram.com/davidperlmutter/Facebook: https://www.facebook.com/DavidPerlmutterMD/YouTube: https://www.youtube.com/@DavidPerlmutterMDX (Twitter): https://x.com/DavidPerlmutter- - - - -PODCASTThank you for listening.Please subscribe and share.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/
