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This Week in Addiction Medicine from ASAM  

This Week in Addiction Medicine from ASAM

Author: American Society of Addiction Medicine

An audio source and summary of the top stories from the field of addiction medicine.
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Language: en

Genres: Health & Fitness, Medicine, Mental Health

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Lead: Methadone Dose and Patient-Directed Discharge in Hospitalized Patients with Opioid Use Disorder
Episode 211
Tuesday, 14 April, 2026

Methadone Dose and Patient-Directed Discharge in Hospitalized Patients with Opioid Use Disorder JAMA Network This retrospective observational cohort study of 554 individuals examined rates of patient-directed discharge (PDD) among hospitalized patients with opioid use disorder who received methadone during the first 72 hours of hospitalization from July 2019 to June 2022. Higher doses of methadone were associated with a decreased rate of PDD. For each additional 10 mg of methadone received in the first 24 hours, there was a decrease in odds of PDD at 48 hours (adjusted OR 0.71). This study highlights the importance of adequate treatment of opioid withdrawal to reduce the risk of PDD.   Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM

 

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