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CNS PodcastCNS Podcast is a podcast broadcasted by the Department of Clinical Neuroscience at Karolinska Institutet. Author: The Department of Clinical Neuroscience, Karolinska Institutet
CNS Podcast is a podcast broadcasted by the Department of Clinical Neuroscience at Karolinska Institutet. To subscribe to our podcast via iTunes please visit https://itunes.apple.com/us/podcast/cns-podcast/id924837042?mt2 Language: en Genres: Health & Fitness, Medicine, Science Contact email: Get it Feed URL: Get it iTunes ID: Get it |
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Episode 4: Targeting the Dopamine System to Treat Alcohol Dependence
Wednesday, 21 October, 2015
In this episode we meet Pia Steensland and Nitya Jayaram-Lindström from the Centre of Psychiatric Research, Department of Clinical Neuroscience to discuss their research on the evaluation of a dopamine stabiliser OSU6162 for alcohol dependence. Their translational studies show that in alcohol dependent patients OSU6162 reduces craving for alcohol and the animal studies demonstrate that OSU6162 normalises the level of dopamine in the brain reward system, following long- term alcohol consumption which could be the mechanism by which this compound mediates in effects. We discuss the implications of these findings for the indication of alcohol dependence and future directions with regards to OSU6162. To read more about on the studie visit http://ki.se/en/news/one-step-closer-to-a-new-drug-for-alcohol-dependence and to read more about their research in general visit http://ki.se/en/cns/johan-francks-research-group
