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The Matt Walker PodcastAuthor: Dr. Matt Walker
The Matt Walker Podcast is all about sleep, the brain, and the body. Matt is a Professor of Neuroscience at the University of California, Berkeley. He is the author of the book, Why We Sleep and has given a few TED talks. Matt is an awkward British nerd who adores science and the communication of science to the public. Language: en-us Genres: Health & Fitness, Medicine, Science, Social Sciences Contact email: Get it Feed URL: Get it iTunes ID: Get it Trailer: |
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#124 - Acting Out Dreams
Monday, 16 February, 2026
Matt delves into the world of REM Sleep Behavior Disorder (RBD), a condition at the frontiers of sleep science. Normally, the brain dreams while atonia paralyzes the body in a neural magic act that is managed by brainstem nuclei activating inhibitory "brakes" in the spinal cord. When this circuit fails, the motor system remains active, enacting nightmares in real-time.RBD is hazardous - 10% of patients sustain injuries requiring medical intervention or hospitalization. It is a prodromal synucleinopathy where misfolded proteins erode the brain's architecture and 50% of patients develop Parkinson’s or Lewy body dementia within a decade. Matt concludes by noting that new skin biopsy biomarkers like Syn-One now offer hope for early detection.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.One of today’s sponsors, LMNT, offers a science-based electrolyte drink with no sugar or artificial ingredients. Try their new limited-time Lemonade Salt flavor! Get eight free sample packs with any order at drinklmnt.com/mattwalker. Stock up on this summer flavor while it lasts!In a supplement industry where trust is critical, Matt uses podcast supporter Puori. Their protein powders are free from hormones, GMOs, and pesticides, with every single batch third-party tested for over 200 contaminants. For protein you can trust, save 20% at puori.com/mattwalker.As always, if you have thoughts or feedback you’d like to share, please reach out:Matt: Instagram @drmattwalker, X @sleepdiplomat, YouTube https://www.youtube.com/@sleepdiplomat
