CogNation

Author: CogNation Media

CogNation is a podcast by Rolf Nelson and Joe Hardy, two cognitive psychologists interested in the future of brain science and technology. We explore relevant topics in the areas of cognitive science, technology, AI, and philosophy. Although we dabble with dystopian implications of new technologies (such as the impending robopocalypse), we are led by our curiosity and try to keep it light and fun. https://www.facebook.com/CognationPodcast/ email: cognationpodcast@gmail.com
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Language: en

Genres: Philosophy, Science, Society & Culture

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Balazs Szigeti: Unblinding Effects in Psychedelic Research
Friday, 24 April, 2026

For the third time, Joe and Rolf talk to Dr. Balazs Szigeti about psychedelics for the treatment of depression. This time, Balazs discusses his recent paper that shows an equivalence between psychedelics and traditional medications in effectiveness for treating depression. This is surprising, given the size of effects that have been demonstrated in some early psychedelic trials, and can be accounted for, in part, by patient expectations.Williams ZJ, Barnett H, Szigeti B. Psychedelic Therapy vs Antidepressants for the Treatment of Depression Under Equal Unblinding Conditions: A Systematic Review and Meta-Analysis. JAMA Psychiatry. Published online March 18, 2026. doi:10.1001/jamapsychiatry.2025.4809