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The Chain: Protein Engineering Podcast  

The Chain: Protein Engineering Podcast

Author: Cambridge Healthtech Institute

The Chain explores the lives, careers, research, and discoveries of protein engineers and scientists, the impact their work is having on the field, and where the industry is headed. Tune in to stay up-to-date on the newest advancements and to hear the stories that are impacting the world of biologics.
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Language: en-us

Genres: Life Sciences, Science

Contact email: Get it

Feed URL: Get it

iTunes ID: Get it


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Episode: 87 - Jack Elands on How Novel ADC Payloads Could Improve Cancer Care
Episode 87
Tuesday, 14 July, 2026

July 14, 2026 | Most ADCs today lean on the same Topo-1 payloads—and resistance is catching up. Jack Elands, Ph.D., founder and CEO of Adcytherix, speaks with host Rakesh Dixit, Ph.D. about what “next-generation ADCs” should mean if we care about patients, not just pipeline counts. Their conversation gets specific about where differentiation comes from: novel payloads with new mechanisms of action, better therapeutic index choices, and smarter design decisions that reduce the toxicities that make patients quit therapy early. They also pressure-test the hype around bispecific ADCs and dual-payload ADCs.  Links from this episode:  Adcytherix 

 

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