The PricePlow Podcast

Supplement Science Podcast Powered by Red Meat and Caffeine

Author: Supplement Industry Thought Leaders

The PricePlow Podcast is the premiere supplement industry podcast, co-hosted by Mike and Ben. We interview various sports nutrition professionals, athletes, and researchers, and entrepeneurs to advance knowledge in active and sports nutrition. As a supplement-centric platform, most of our episodes revolve around sports nutrition supplements and performance enhancement, but we wont limit our guests to that! Videos, write-ups, and citations can be found at the accompanying blog posts on https://blog.PricePlow.com/podcast
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Genres: Alternative Health, Health & Fitness, Nutrition

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#206: Paul Eftang & Matt Harrier - Nootropics Depot Against the World, Part 2: The Product Line
Episode 206
Thursday, 26 February, 2026

If you thought Part 1 with Paul Eftang and Matt Harrier was wild — an FDA raid with guns drawn, two years of legal battles, and a crusade against supplement fraud — Part 2 is where it gets genuinely useful. Episode #206 of the PricePlow Podcast picks up right where we left off, this time diving deep into the actual ingredients and products that Nootropics Depot has developed, sourced, and standardized over more than a decade of pharmaceutical-grade R&D. Recorded at Nootropics Depot’s headquarters in Tempe, Arizona, Paul and Matt walk us through tongkat ali’s redemption arc from “gas station boner pill” to clinically meaningful testosterone support, explain why almost every mushroom supplement on the market is mislabeled, detail a 6-year journey to bring a real Ecklonia cava to market, and reveal how a bacopa extract binds to the same receptor as psilocybin. Along the way, they cover cistanche, lion’s mane, Tribugen, a prebiotic fiber system, a novel protein concept, and an industry-wide testing fraud landscape that makes their product philosophy make total sense. Sign up for Nootropics Depot news alerts on PricePlow and subscribe to the PricePlow Podcast on your favorite platform before diving in. https://blog.priceplow.com/podcast/nootropics-depot-products-206 Video: Paul Eftang and Matt Harrier of Nootropics Depot Break Down the Products https://www.youtube.com/watch?v=LkZ-GDzEQRo Detailed Show Notes: Paul Eftang and Matt Harrier of Nootropics Depot on Ingredients, Innovation, and Industry Fraud (0:00) – Introductions (0:15) – Tongkat Ali: From “Gas Station Boner Pill” to Top Seller (7:30) – The TRT Problem: Are Doctors Telling Men They’re Broken? (10:30) – EurycoMax: The Optimized Tongkat Ali Stack (12:00) – Lance Dreher: A 70-Year-Old Mr. Universe Case Study (14:30) – Cell Culture Research at Nootropics Depot (17:45) – Lion’s Mane: The Mycelium vs. Fruiting Body Debate (23:45) – Building Reference Standards from Scratch (26:30) – Erinamax: The World’s First Erinacine A Product (28:30) – Nerve Growth Factor and Real Consumer Stories (30:45) – Tiger Milk Mushroom and Traditional Wisdom (36:30) – Ecklonia Cava: A 6-Year Quest (44:00) – Dieckol: The UV Protection Discovery (47:00) – Why Most Ecklonia Cava on the Market Is Fake (52:00) – Consumer Expectations vs. Long-Term Ingredient Reality (55:00) – Cistanche: The Most Underrated Ingredient (59:15) – Cognance: Bacopa Reinvented with Ebelin Lactone (1:01:30) – Solving Bacopa Anhedonia (1:03:00) – The Sabroxy-Cognance-Saffron Stack (1:05:00) – Infinifiber and the Akkermansia Ecosystem (1:10:15) – The Protein Frontier and Future Ingredients (1:16:15) – AI as an R&D Tool (1:21:15) – Tribulus, Protodiosein, and the DHT Angle (1:22:45) – The Turkesterone ExposÃ© (1:29:00) – Amazon Fraud and Industry-Wide Testing Failures (1:31:30) – Third-Party Lab Shopping and Dry Labs Where to Follow and Learn More Connect with Paul Eftang, Matt Harrier, and Nootropics Depot Matt Harrier … Read more on the PricePlow Blog